Oral paracoccidioidomycosis: a case report
Gabriel Melo Caldas Nogueira, Eduardo Otto Gomes, Emerson Kennedy Ribeiro de Andrade Filho, Sheila Ramos de Miranda Henriques, Marina Mayara Batista do Rêgo
Abstract
Paracoccidioidomycosis (PCM) is a mycosis caused by fungi of the genus Paracoccidioides. Although it is rare globally, PCM is especially prevalent in Latin America, with 10 million infected individuals. Notably, approximately 80% of these cases are in Brazil, where PCM accounts for the highest mortality rate among systemic mycoses. Annual incidence estimates of PCM in Brazil range from 0.71 to 3.70 cases per 100,000 inhabitants. There is an important relationship between PCM and agriculture, since the soil serves as a reservoir for the microorganism. The fungus is primarily contracted through inhalation. In about 5% of patients, the disease may progress to an acute/subacute or chronic state, affecting various organs, including the oral cavity. Oral lesions are observed in about 60% of diagnosed individuals and are more prevalent in middleaged and elderly males. This report presents a case of a 58-year-old man with a PCM lesion on his soft palate.
Keywords
References
1. Hahn RC, Hagen F, Mendes RP, Burger E, Nery AF, Siqueira NP, Guevara A, Rodrigues AM, Camargo ZP. Paracoccidioidomycosis: current status and future trends. Clin Microbiol Rev. 2022;35(4):e0023321. http://dx.doi.org/10.1128/ cmr.00233-21. PMid:36074014.
2. Oliveira LLC, Arruda JAA, Marinho MFP, Cavalcante IL, Abreu LG, Abrahão AC, Romañach MJ, Andrade BAB, Agostini M. Oral paracoccidioidomycosis: a retrospective study of 95 cases from a single center and literature review. Med Oral Patol Oral Cir Bucal. 2023;28(2):e131-9. http://dx.doi.org/10.4317/ medoral.25613. PMid:36806021.
3. Shikanai-Yasuda MA, Mendes RP, Colombo AL, Telles FQ, Kono A, Paniago AMM, Nathan A, Valle ACFD, Bagagli E, Benard G, Ferreira MS, Teixeira MM, Vergara MLS, Pereira RM, Cavalcante RS, Hahn R, Durlacher RR, Khoury Z, Camargo ZP, Moretti ML, Martinez R. II Consenso Brasileiro em Paracoccidioidomicose - 2017. Epidemiol Serv Saude. 2018;27(Spe):e0500001. http://dx.doi.org/10.5123/S1679-
49742018000500001. PMid:30133688.
4. Colombo AL, Tobón AM, Restrepo A, Queiroz-Telles F, Nucci M. Epidemiology of endemic systemic fungal infections in Latin America. Med Mycol. 2011;49(8):785-
98. http://dx.doi.org/10.3109/13693786.2011.577821. PMid:21539506.
5. Dutra LM, Silva THM, Falqueto A, Peçanha PM, Souza LRM, Gonçalves SS, Velloso TRG. Oral paracoccidioidomycosis in a single-center retrospective analysis from a Brazilian southeastern population. J Infect Public Health. 2018;11(4):530-3. http://dx.doi.org/10.1016/j.jiph.2017.10.009. PMid:29153538.
Submitted date:
07/05/2023
Accepted date:
09/07/2023
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